Reportlab is my go-to PDF library in python; however, it doesn’t do multiple page layout well. The solution is to do regular multiple pages PDF with reportlab, then process that PDF file afterward to have any layout you want (2-page per sheet, 4-page per sheet, 9-page per sheet, …)

What you need?

pdfnup – it’s available via pip but an ImportError always there. As a result, you need to download that and do install by yourself.

$ python setup.py install

Simple enough. You also have a command line to work on too.

>>> from pdfnup import generateNup
>>>
>>> generateNup("multiple-pages.pdf", 2, verbose=True)
written: file-2up.pdf

There you go.